The Global. If the river makes a noise its because water is running. For several years now, both politicians and the pharmaceutical sector and lawyers have been calling for greater legislative clarity in relation to biological medicines. Between ministerial orders (in 2007 one was promulgated to ensure non-substitution), the Guarantees Law (where some jurists such as Sánchez Fierro see contradictions) and European directives, the current legislation leads to confusion between the sector and the administrations.

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